Apoptosis Reagents and Kits
Eurofins Discoverx KILR NCI-H292 (Human) Cytotoxicity Assay Kit (cell pool)
The KILR NCI-H292 (Human) Stable Cell Pool Cytotoxicity Assay utilizes the engineered stable target cell pool that is used to measure direct death mediated by immuno-oncology treatments via ADCC, CDC, and ADCP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Apexbio Technology LLC Selective Bcl-2 inhibitor 1257044-40-8. MFCD23160052
Selective Bcl-2 inhibitor 1257044-40-8. MFCD23160052
Eurofins Discoverx KILR EL4 (Mouse) Cytotoxicity Assay Kit (cell pool)
The KILR EL4 (Mouse) Stable Cell Pool Cytotoxicity Assay utilizes the engineered stable target cell pool that is used to measure direct death mediated by immuno-oncology treatments via ADCC, CDC, and ADCP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Abcam Human RAB9A (Rab9) knockout HeLa cell lysate.
Human RAB9A (Rab9) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human CHEK2 (Chk2) knockout HeLa cell lysate.
Human CHEK2 (Chk2) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
CPC Scientific Ac-Trp-Glu-His-Asp-CHO (trifluoroacetate salt) 1MG
Very potent reversible inhibitor of caspase-1 (ICE) that contains the optimal tetrapeptide recognition motif for this enzyme. With a Ki of 56 pM, it displays the most potent reversible, peptide-based inhibitors described for any protease. For caspase-8 a Ki of 21.1 nM has been reported.SEQUENCE: Ac-Trp-Glu-His-Asp-CHO (trifluoroacetate salt)ONE-LETTER SEQUENCE: Ac-WEHD-CHOMOLECULAR FORMULA: C28H33N7O9MOLECULAR WEIGHT: 611.61STORAGE CONDITIONS: -20 5 CCAS REGISTRY NUMBER: [189275-71-6]SYNONYMS: Ac-Trp-Glu-His-Asp-aldehyde (pseudo acid)RESEARCH AREA: ApoptosisREFERENCES:T.A. Rano, T. Timkey, E.P. Peterson, J. Rotonda, D.W. Nicholson, J.W. Becker, K.T. Chapman, and N.A. Thornberry, Chem. Biol., 4, 149 (1997).M. Garcia-Calvo, E.P. Peterson, B. Leiting, R. Ruel, D.W. Nicholson, and N.A. Thornberry, J. Biol. Chem., 273, 32608 (1998).SKU(s): CASP-004A
Abcam Annexin V-iFluor 594 Apoptosis Staining / Detection Reagent.
Annexin V-iFluor 594 Apoptosis Staining / Detection Reagent.
The product is subject to the following: Abcam Restricted Use Statement
AdipoGen WP1130
Chemical. CAS 856243-80-6. Formula C19H18BrN3O. MW 384.3. WP1130 is a second-generation tyrphostin derivative initially identified as a JAK2 signaling inhibitor through JAK2 ubiquitination that reduces STAT activation stimulated by cytokines such as IL-6 and IL-3 through the rapid down-regulation of upstream JAK kinases. WP1130 has also been identified as a partially selective cell permeable deubiquitinating enzyme/deubiquitinase DUB inhibitor that directly inhibits DUB activity of USP9x, USP5, USP14, USP24, UCH37, UCHL1 and UCHL5, leading to rapid accumulation of polyubiquitinated K48/K63-linked proteins into juxtanuclear aggresomes and tumor cell apoptosis, accounting for its anti-cancer properties. Through this mechanism, WP1130 has been shown to downregulate the antiapoptotic proteins Bcr/Abl and Jak2 and to upregulate the proapoptotic proteins MCL-1 and p53.
Medchemexpress LLC Annexin A1/ANXA1 Mo 1mg
Annexin A1 (ANXA1) Protein, Mouse (His) is a full-length recombinant mouse annexin A1 expressed in Escherichia coli with an N-terminal 6xHis tag, supplied as a lyophilized powder. The protein is >95% pure, has an approximate molecular weight of 40 kDa, and low endotoxin (<1 EU/μg); it is formulated with trehalose for stability and intended for in vitro studies of inflammation, immune signaling, phagocytosis, and chemotaxis.
- Full-length recombinant protein with N-terminal His tag.
- Expressed in Escherichia coli for scalable production.
- Purity greater than 95% by reducing SDS-PAGE.
- Approximately 40 kDa molecular weight.
- Low endotoxin level (<1 EU/μg) suitable for cell-based assays.
- Lyophilized formulation with trehalose for enhanced stability.
- Demonstrated biological activity in suppressing TNF-alpha secretion in RAW264.7 cells.
- Multiple size options available to fit experimental needs.
Abcam Human DAB2 knockout HeLa cell lysate.
Human DAB2 knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Bioss Annexin A10 Monoclonal Antibod
Annexin A10 Primary Antibody Unconjugated Host Species Rabbit Target Species Human Mouse Rat Clonality Monoclonal Applications WB RecombinantConcentration 1ug/ul Size 100 ul Storage Buffer 10mM phosphate buffered saline(pH 7 4) with 150mM sodium chloride 0 05% BSA 0 02% sodium azide and 50% glycerol
Abcam Phalloidin-iFluor 750 Reagent.
Phalloidin-iFluor 750 Reagent.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human HK2 (Hexokinase II) knockout HEK-293 cell lysate.
Human HK2 (Hexokinase II) knockout HEK-293 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement