Apoptosis Reagents and Kits
Biotium JC-1 Mitochondrial Membrane Potential Detection Kit (100 assays)
The loss of mitochondrial membrane potential is a hallmark for apoptosis. It is an early event preceding phosphatidylserine externalization and coinciding with caspase activation. JC-1 Mitochondrial Membrane Potential Detection Kit is used to measure mitochondrial membrane potential changes in cells. In non-apoptotic cells, JC-1 accumulates as aggregates in the mitochondrial membranes, resulting in red fluorescence (590 nm). The brightness of red fluorescence is proportional to the potential and varies among different cell types. However, in apoptotic and necrotic cells, which have diminished mitochondrial membrane potential, JC-1 exists in the green fluorescent (529 nm) monomeric form. This kit provides a step-by-step protocol and ready-to-use reagents for performing assays for flow cytometry, fluorescence microscopy, or fluorometric microplate reader.
Medchemexpress LLC N-(Benzyloxycarbonyl)-D-homoserine | 41088-85-1 | MFCD12545887 | 253.25 | C12H15NO5 | 1 G
N-(Benzyloxycarbonyl)-D-homoserine is the D-enantiomer of homoserine bearing an N-carbobenzoxy (Cbz) protecting group. Supplied as a powder, it is used as a drug intermediate in small-molecule synthesis and can be employed in the preparation of antibody-drug conjugates (ADCs). Molecular formula C12H15NO5; molecular weight 253.25. Recommended storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Protected amino group enables selective synthetic transformations.
- Suitable for use as a drug intermediate in medicinal chemistry workflows.
- Powder form supports convenient handling and long-term storage.
- Defined molecular formula and mass aid analytical characterization.
- Established storage recommendations help preserve compound stability.
Abcam P7C3, pro-neurogenic and neuroprotective compound, 10MG
MW 474.2 Da, Purity >99%. Pro-neurogenic and neuroprotective compound. Blocks apoptosis of newborn neurons of the dentate gyrus. Also protects mature neurons. Enhances neurogenesis and additionally improves cognitive behaviour. Blood-brain barrier permeable. Active in vivo.
The product is subject to the following: Abcam Restricted Use Statement
American Research Products Inc AMERICAN RESEARCH PRODUCTS INC
5000631184 PORCINE CASPASE-3 ELISA KIT
TRIBIOSCIENCE INC Caspase-3 Colorimetric Assay Kit, 100 Tests
Caspase-3 Colorimetric Assay provides a simple and convenient approach for assaying the activity of caspases that recognize the sequence DEVD. The assay is based on spectrophotometric detection of the chromophore p-nitroaniline (pNA) after cleavage from the labeled substrate DEVD-pNA. The pNA light emission can be quantified using a spectrophotometer or a microtiter plate reader at 400- or 405-nm.
AdipoGen Hoechst 33342
Chemical. CAS 23491-52-3. Formula C27H28N6O . 3HCl . xH2O. MW 561.93. Synthetic. Useful for staining DNA, chromosomes and nuclei. May be used for fluorescence microscopy or flow cytometry. Suitable for vital DNA staining of a variety of cell types and as a probe of membrane permeability in mammalian cells.
Medchemexpress LLC N-carbobenzoxy-D-homoserine | 41088-85-1 | MFCD12545887 | 253.25 g/mol | C12H15NO5 | 5 G
N-Carbobenzoxy-D-homoserine (N-(Benzyloxycarbonyl)-D-homoserine) is the D-enantiomer of homoserine bearing an N-carbobenzoxy (Cbz) protecting group. Supplied as a powder, it is used as a synthetic intermediate in organic and peptide synthesis, including preparation of antibody-drug conjugates and other constructs that require temporary N-protection.
- Powdered synthetic intermediate for organic synthesis.
- Contains N-carbobenzoxy (Cbz) protecting group for the amino function.
- Suitable for peptide synthesis and antibody-drug conjugate payload or linker preparation.
- Molecular formula C12H15NO5; molecular weight 253.25 g/mol.
- Recommended storage: powder -20°C for long term, 4°C for short term.
Medchemexpress LLC Recombinant human annexin A5 (ANXA5) | >95.0% | 5 UG
Recombinant human Annexin A5 (ANXA5) supplied as a lyophilized protein for research use. This calcium-dependent phospholipid-binding protein is commonly used as an apoptosis marker and in studies of membrane dynamics. Supplied as a 5 μg vial with characterization data for purity and molecular weight.
Biolegend APC Annexin V Apoptosis Detection Kit with 7-AAD
APC Annexin V Apoptosis Detection Kit with 7-AAD Reactivity: All mammalian species; Apps: FC; Size: 100 tests
Biolegend Pacific Blue™ Annexin V Apoptosis Detection Kit with PI
Pacific Blue™ Annexin V Apoptosis Detection Kit with PI Reactivity: All mammalian species; Apps: FC; Size: 100 tests
Meso Scale Discovery R-PLEX Human Annexin A5 ASY
The R-Plex Human Annexin A5 Assay from Meso Scale Diagnostics is a multiplex immunoassay that measures Annexin A5 levels in human serum plasma and cell culture supernatants It utilizes electrochemiluminescence (ECL) detection technology and provides high sensitivity broad dynamic range and requires low sample volume This assay allows for the quantitative measurement of Annexin A5 an important biomarker for apoptosis It can be used to monitor cell death and apoptosis signaling in disease research drug discovery development and clinical research This multiplexed assay enables efficient and accurate analysis of Annexin A5 levels
Abcam Boc-D-FMK, caspase inhibitor, 1MG
MW 263.26 Da. Irreversible general caspase inhibitor. Blocks hepatocyte apoptosis in vivo. Active in vitro and in vivo. Cell-permeable.
The product is subject to the following: Abcam Restricted Use Statement
American Research Products Inc PrEST Antigen CASP9
PrEST Antigen CASP9 antigen APrEST87471 for caspase 9 apoptosis-related cysteine peptidase Recombinant protein fragment of Human CASP9